| 🇦🇪Abu DhabiAUH | Air Arabia Abu Dhabi, Etihad Airways | — | 12x weekly | 2,309 km | Details |
| 🇰🇿AlmatyALA | Taban Airlines, Uzbekistan Airways, Air Astana | — | Daily+ | 679 km | Details |
| 🇯🇴AmmanAMM | Royal Jordanian | — | 3x weekly | — | Details |
| 🇺🇿AndijanAZN | Uzbekistan Airways, AtlasGlobal UA | — | 9x weekly | 260 km | Details |
| 🇹🇷AnkaraESB | Uzbekistan Airways, AJet | — | 13x weekly | 3,040 km | Details |
| 🇹🇷AntalyaAYT | Taban Airlines, Uzbekistan Airways | — | Daily+ | — | Details |
| 🇷🇺ArtyomVVO | Uzbekistan Airways | — | 1x weekly | 5,048 km | Details |
| 🇰🇿AstanaNQZ | Fly Arystan, Uzbekistan Airways, Air Astana | — | Daily+ | 1,099 km | Details |
| 🇵🇰AttockISB | Uzbekistan Airways | — | 2x weekly | 912 km | Details |
| 🇦🇿BakuGYD | Elite Airways, Uzbekistan Airways, AZAL Azerbaijan Airlines | — | Daily+ | 1,617 km | Details |
| 🇹🇭BangkokBKK | Uzbekistan Airways | — | 3x weekly | 4,318 km | Details |
| 🇬🇪BatumiBUS | Uzbekistan Airways | — | 8x weekly | — | Details |
| 🇨🇳BeijingPKX | China Southern Airlines, Taban Airlines, Uzbekistan Airways | — | 9x weekly | 3,948 km | Details |
| 🇨🇳BeijingPEK | Air China, Uzbekistan Airways | — | 3x weekly | 3,942 km | Details |
| 🇰🇬BishkekBSZ | Uzbekistan Airways, Cathay Dragon | — | Daily+ | 473 km | Details |
| 🇹🇷BodrumBJV | Uzbekistan Airways | — | 3x weekly | — | Details |
| 🇺🇿BukharaBHK | Uzbekistan Airways, AtlasGlobal UA | — | Daily+ | 438 km | Details |
| 🇰🇷BusanPUS | Taban Airlines | — | 1x weekly | 5,153 km | Details |
| 🇨🇳Chengdu (Jianyang)TFU | Loong Air | — | 3x weekly | 3,369 km | Details |
| 🇹🇷DalamanDLM | Uzbekistan Airways | — | 1x weekly | — | Details |
| 🇶🇦DohaDOH | Qatar Airways | — | 4x weekly | 2,411 km | Details |
| 🇦🇪DubaiDXB | flydubai, Uzbekistan Airways | — | Daily+ | 2,194 km | Details |
| 🇦🇪Dubai(Jebel Ali)DWC | Taban Airlines | — | 6x weekly | 2,239 km | Details |
| 🇹🇯DushanbeDYU | Uzbekistan Airways, Somon Air | — | 9x weekly | 304 km | Details |
| 🇺🇿FerganaFEG | Uzbekistan Airways, AtlasGlobal UA | — | Daily+ | 230 km | Details |
| 🇮🇹Ferno (VA)MXP | Taban Airlines, Uzbekistan Airways | — | 3x weekly | 4,796 km | Details |
| 🇩🇪Frankfurt am MainFRA | Taban Airlines, Uzbekistan Airways | — | Daily | 4,685 km | Details |
| 🇹🇷GaziemirADB | Sun Express | — | 2x weekly | — | Details |
| 🇷🇺GroznyGRV | Uzbekistan Airways | — | 5x weekly | 1,947 km | Details |
| 🇨🇳Guangzhou (Huadu)CAN | China Southern Airlines, Uzbekistan Airways | — | 12x weekly | 4,527 km | Details |
| 🇨🇳HangzhouHGH | Uzbekistan Airways | — | 3x weekly | 4,705 km | Details |
| 🇷🇺IrkutskIKT | Uzbekistan Airways, Ural Airlines | — | 4x weekly | 2,904 km | Details |
| 🇹🇷IstanbulIST | Taban Airlines, Uzbekistan Airways, Turkish Airlines | — | Daily+ | 3,358 km | Details |
| 🇸🇦JeddahJED | Elite Airways, Southern Air, Uzbekistan Airways +1 | — | Daily | 3,561 km | Details |
| 🇦🇫KabulKBL | Kam Air | — | 2x weekly | 744 km | Details |
| 🇷🇺KazanKZN | Elite Airways, Uzbekistan Airways, Nordwind Airlines +1 | — | 11x weekly | 2,158 km | Details |
| 🇷🇺KhabarovskKHV | Uzbekistan Airways | — | 1x weekly | 5,091 km | Details |
| 🇷🇺KrasnodarKRR | Azimuth Airlines, Uzbekistan Airways | — | 1x weekly | 2,464 km | Details |
| 🇷🇺KrasnoyarskKJA | Rossiya Airlines, Uzbekistan Airways, Ural Airlines | — | 8x weekly | 2,355 km | Details |
| 🇰🇼Kuwait CityKWI | Jazeera Airways | — | 2x weekly | 2,342 km | Details |
| 🇬🇧LondonLGW | Taban Airlines, Uzbekistan Airways | — | 4x weekly | — | Details |
| 🇬🇧LondonLHR | Uzbekistan Airways | — | 3x weekly | 5,261 km | Details |
| 🇷🇺MakhachkalaMCX | Uzbekistan Airways, Red Wings | — | 2x weekly | 1,790 km | Details |
| 🇲🇻MaléMLE | | — | 3x weekly | 4,143 km | Details |
| 🇸🇦MedinaMED | Sun d'Or, Elite Airways, flyadeal +1 | — | Daily | 3,302 km | Details |
| 🇷🇺Mineralnyye VodyMRV | Azimuth Airlines, Uzbekistan Airways | — | 6x weekly | 2,155 km | Details |
| 🇧🇾MinskMSQ | Belavia, Uzbekistan Airways | — | Daily | 3,337 km | Details |
| 🇮🇳MopaGOX | Uzbekistan Airways | — | 1x weekly | 2,871 km | Details |
| 🇷🇺MoscowVKO | Elite Airways, Pobeda, Uzbekistan Airways +1 | — | Daily+ | 2,811 km | Details |
| 🇷🇺MoscowSVO | Aeroflot | — | Daily+ | 2,818 km | Details |
| 🇷🇺MoscowDME | Taban Airlines, Uzbekistan Airways | — | Daily | 2,766 km | Details |
| 🇷🇺MoscowZIA | Ural Airlines | — | 4x weekly | 2,757 km | Details |
| 🇮🇳MumbaiBOM | Uzbekistan Airways | — | 2x weekly | 2,488 km | Details |
| 🇩🇪MunichMUC | Uzbekistan Airways | — | 3x weekly | 4,495 km | Details |
| 🇴🇲Muscat/SeebMCT | Oman Air | — | 2x weekly | — | Details |
| 🇺🇿NamanganNMA | Taban Airlines, Uzbekistan Airways, AtlasGlobal UA | — | Daily | 193 km | Details |
| 🇯🇵NaritaNRT | Uzbekistan Airways | — | 2x weekly | 6,042 km | Details |
| 🇺🇿NavoiNVI | AtlasGlobal UA | — | 5x weekly | — | Details |
| 🇮🇳New DelhiDEL | Uzbekistan Airways | — | Daily+ | 1,580 km | Details |
| 🇺🇸New YorkJFK | Uzbekistan Airways | — | 6x weekly | 10,176 km | Details |
| 🇻🇳Nha Trang/nha Trang aiurportCam RanhCXR | Taban Airlines, Uzbekistan Airways | — | 10x weekly | — | Details |
| 🇷🇺NizhnevartovskNJC | Pobeda, Uzbekistan Airways, Ural Airlines | — | 2x weekly | 2,243 km | Details |
| 🇷🇺Nizhny NovgorodGOJ | Uzbekistan Airways | — | 5x weekly | 2,477 km | Details |
| 🇷🇺NovosibirskOVB | Uzbekistan Airways, S7 Airlines | — | 12x weekly | 1,816 km | Details |
| 🇺🇿NukusNCU | Uzbekistan Airways | — | Daily+ | 811 km | Details |
| 🇫🇷Paris (Roissy-en-France, Val-d'Oise)CDG | Uzbekistan Airways | — | 2x weekly | 5,133 km | Details |
| 🇷🇺PermPEE | UVT Aero | — | 1x weekly | 2,076 km | Details |
| 🇻🇳Phu Quoc IslandPQC | Taban Airlines, Uzbekistan Airways | — | Daily | 4,843 km | Details |
| 🇹🇭PhuketHKT | Taban Airlines, Uzbekistan Airways | — | 5x weekly | 4,664 km | Details |
| 🇨🇿PraguePRG | Taban Airlines | — | 1x weekly | — | Details |
| 🇱🇻RigaRIX | Elite Airways, Uzbekistan Airways | — | 6x weekly | 3,641 km | Details |
| 🇮🇹RomeFCO | Uzbekistan Airways | — | 2x weekly | — | Details |
| 🇷🇺SamaraKUF | Uzbekistan Airways, Aeroflot, Red Wings | — | 4x weekly | 1,970 km | Details |
| 🇺🇿SamarkandSKD | Uzbekistan Airways, AtlasGlobal UA | — | Daily+ | 260 km | Details |
| 🇨🇳Sanya (Tianya)SYX | Taban Airlines | — | 1x weekly | 4,578 km | Details |
| 🇰🇷SeoulICN | Taban Airlines, Uzbekistan Airways, Asiana Airlines +1 | — | Daily+ | 4,844 km | Details |
| 🇲🇾SepangKUL | Malindo Air, AirAsia X, Uzbekistan Airways | — | 6x weekly | 5,369 km | Details |
| 🇨🇳Shanghai (Pudong)PVG | China Eastern Airlines | — | 4x weekly | — | Details |
| 🇦🇪SharjahSHJ | Air Arabia | — | 8x weekly | 2,179 km | Details |
| 🇪🇬Sharm El SheikhSSH | Sun d'Or, Taban Airlines, Uzbekistan Airways | — | 10x weekly | 3,487 km | Details |
| 🇷🇺SochiAER | Azimuth Airlines, Uzbekistan Airways | — | 2x weekly | 2,409 km | Details |
| 🇷🇺St. PetersburgLED | Rossiya Airlines, Taban Airlines, Uzbekistan Airways +1 | — | Daily+ | 3,365 km | Details |
| 🇷🇺SurgutSGC | UTAir | — | 1x weekly | 2,250 km | Details |
| 🇬🇪TbilisiTBS | Uzbekistan Airways | — | Daily | 2,021 km | Details |
| 🇮🇱Tel AvivTLV | Taban Airlines, Uzbekistan Airways | — | 3x weekly | 3,212 km | Details |
| 🇺🇿TermezTMJ | Sun d'Or, Uzbekistan Airways, AtlasGlobal UA | — | Daily+ | 473 km | Details |
| 🇷🇺TyumenTJM | UTAir | — | 2x weekly | 1,793 km | Details |
| 🇷🇺UfaUFA | Uzbekistan Airways, UTAir | — | 5x weekly | 1,778 km | Details |
| 🇺🇿UrgenchUGC | Sun d'Or, Uzbekistan Airways | — | Daily+ | 721 km | Details |
| 🇨🇳ÜrümqiURC | Air China, China Southern Airlines, Uzbekistan Airways | — | Daily+ | 1,516 km | Details |
| 🇵🇱WarsawWAW | LOT - Polish Airlines | — | 6x weekly | 3,798 km | Details |
| 🇨🇳Xianyang (Weicheng)XIY | Loong Air, China Eastern Airlines | — | 6x weekly | 3,516 km | Details |
| 🇷🇺YekaterinburgSVX | Elite Airways, Uzbekistan Airways, Ural Airlines | — | 9x weekly | 1,826 km | Details |
| 🇦🇲YerevanEVN | FlyOne Armenia, Shirak Avia | — | 4x weekly | — | Details |
| 🇺🇿ZaaminOMN | AtlasGlobal UA | — | 5x weekly | 157 km | Details |
| 🇧🇪ZaventemBRU | Uzbekistan Airways | — | 1x weekly | 4,944 km | Details |
